Biology B
Content of GCSE Biology B
3.1 Summary of content
The specification content is presented as six modules which are listed below. Within each module the content is shown as eight items (e.g., B1a, B1b, B1c, B1d, B1e, B1f, B1g and B1h). Thus, the specification content contains a total of 48 teaching items. Each item requires approximately 2½ hours teaching time.
Module B1: Understanding Organisms Module
- Fitness and health
- Human health and diet
- Staying healthy
- The nervous system
- Drugs and you
- Staying in balance
- Controlling plant growth
- Variation and inheritance
B2: Understanding Our Environment Module
- Classification
- Energy flow
- Recycling
- Interdependence
- Adaptations
- Natural selection
- Population and pollution
- Sustainability
B3: Living And Growing
- Molecules of life
- Proteins and mutations
- Respiration
- Cell division
- The circulatory system
- Growth and development
- New genes for old
- Cloning
Module B4: It’s A Green World Module
- Ecology in the local environment
- Photosynthesis
- Leaves and photosynthesis
- Diffusion and osmosis
- Transport in plants
- Plants need minerals
- Decay
- Farming
B5: The Living Body Module
- Skeletons
- Circulatory systems and the cardiac cycle
- Running repairs
- Respiratory systems
- Digestion
- Waste disposal
- Life goes on
- Growth and repair
B6: Beyond The Microscope
- Understanding microbes
- Harmful microorganisms
- Useful microorganisms
- Biofuels
- Life in soil
- Microscopic life in water
- Enzymes in action
- Gene technology
Module B1: Understanding Organisms
Item B1a: Fitness and health
Summary: This item looks at the differences between health and fitness, concentrating on the causes and prevention of heart disease, which is the most common cause of death in the UK.
Suggested practical and research activities to select from |
Assessable learning outcomes Foundation Tier only: low demand |
Measure blood pressure. |
Explain why blood in arteries is under pressure: • due to contraction of heart muscles • so that it reaches all parts of the body. |
Visit a fitness centre, or have a visit from a representative and prepare a report on an individual fitness programme, including how ICT is used in assessing and monitoring fitness. |
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Use websites to plan for a lower cholesterol intake. Produce a poster or leaflet encouraging a healthy lifestyle to reduce the risk of heart disease. |
Recognise that the risk of developing heart disease can be increased by a number of factors, to include:
• high blood pressure • smoking • eating high levels of salt • eating high levels of saturated fat.
Describe how cholesterol can restrict or block blood flow in arteries by forming plaques. Analyse data that show the changing incidence of heart disease in the UK. |
Module B1: Understanding Organisms
Item B1a: Fitness and health
Assessable learning outcomes both tiers: standard demand |
Assessable learning outcomes Higher Tier only: high demand |
Recall that blood pressure measurements consist of diastolic and systolic data in mmHg.
Describe the factors that increase blood pressure:
• being overweight • stress • high alcohol intake • smoking.
Describe the factors that decrease blood pressure:
• regular exercise • balanced diet. |
Explain the possible consequences of having high blood pressure.
Explain the possible consequences of having low blood pressure. |
Explain the difference between fitness (the ability to do physical activity) and health (free from disease).
Analyse the results of different ways of measuring fitness (strength, stamina, flexibility, agility, speed and cardiovascular efficiency). |
Evaluate different ways of measuring fitness. |
Explain how smoking increases blood pressure:
• carbon monoxide reduces the oxygen-carrying capacity of the blood so heart rate increases to compensate
• nicotine increases heart rate.
Explain how diet can increase the risk of heart disease to include:
• saturated fats leading to a build up of cholesterol (a plaque) in arteries
• high levels of salt elevating blood pressure.
Interpret data showing possible links between the amount of saturated fat eaten, the build up of cholesterol plaques and the incidence of heart disease. |
Explain why carbon monoxide reduces the carrying capacity of red blood cells, using the idea that it combines with the haemoglobin preventing the oxygen transport.
Explain how narrowed coronary arteries, together with a thrombosis, increase the risk of a heart attack. |
Module B1: Understanding Organisms
Item B1b: Human health and diet
Summary: The populations of many countries are either underweight and starving or obese with associated health problems. This item looks at food as a source of energy and raw materials and considers the effects of diet on candidates’ bodies. This item provides the opportunity to collect and analyse scientific data from primary and secondary sources, including the use of ICT tasks, when investigating individuals’ energy intake and countries facing food emergencies. Research on countries having food emergencies provides the opportunity to discuss ethical issues raised by science and technology.
Suggested practical and research activities to select from |
Assessable learning outcomes Foundation Tier only: low demand |
Compare the nutritional value of various breakfast cereals.
Record a day’s food intake and calculate the total energy intake.
Investigate energy content in various foods.
Carry out simple food tests on a variety of food types. |
Explain why a balanced diet should include:
• protein • carbohydrates and fats • minerals (limited to iron) • vitamins (limited to vitamin C) • fibre • water. |
Use ICT tasks, including video clips, to research
countries having food emergencies and facing starvation.
Calculate personal estimated average daily requirement (EAR) for protein.
Record a day’s food intake and calculate the amount of protein.
Calculate a Body Mass Index (BMI) and use provided information to make a decision as to what it indicates. |
Interpret simple data on diet.
Explain why:
• a high protein diet is necessary for teenagers • in many parts of the world diets are deficient in protein.
Recall that proteins are only used as an energy source when fats or carbohydrates are unavailable.
Recall that being very overweight (obese) is linked to increased health risks, to include arthritis, heart disease, diabetes and breast cancer. |
Module B1: Understanding Organisms
Item B1b: Human health and diet
Assessable learning outcomes both tiers: standard demand |
Assessable learning outcomes Higher Tier only: high demand |
Recall that:
• carbohydrates are made up of simple sugars such as glucose • fats are made up of fatty acids and glycerol • proteins are made up of amino acids.
Explain how a balanced diet will vary depending on age, gender, activity, religion, personal choice (to include vegetarians and vegans) and medical issues (to include food allergies). |
Describe the storage of biological molecules, to include:
• carbohydrates are stored in the liver as glycogen or converted to fats • fats are stored under the skin and around organs as adipose tissue • proteins are not stored. |
Explain why protein deficiency (kwashiorkor) is common in developing countries, limited to:
• overpopulation • limited investment in agricultural techniques.
Calculate the estimated average daily requirement (EAR) for protein using the formula: EAR in g = 0.6 × body mass in kg Calculate the Body Mass Index given the formula: BMI = mass in kg/(height in m)2 and use it as a guide to understand the terms underweight, normal, overweight and obese.
Explain how low self-esteem, poor self-image and desire for perfection can lead to a poor diet and the increased risks involved. |
Explain why vegetarians need to eat proteins from a wide range of sources compared to people who eat proteins of animal origin.
Understand that the EAR is an estimated daily figure for an average person of a certain body mass.
Explain why the EAR for protein may vary depending on age, pregnancy and lactation. |
Module B1: Understanding Organisms
Item B1c: Staying healthy
Summary: This item aims to help candidates understand the causes, preventative measures and cures of some diseases, while understanding that not all diseases are easily controlled or cured. This item provides the opportunity to analyse, interpret, apply and question scientific information and ideas, including some questions that science cannot currently answer in cancer treatment and drug testing. These topics also allow candidates to discuss ethical issues raised and develop the skills of scientific argument and presentation of data.
Suggested practical and research activities to select from |
Assessable learning outcomes Foundation Tier only: low demand |
Carry out a survey of diseases suffered by candidates in a class or year (limited to flu/colds, athlete’s foot and ‘stomach upsets’) using primary or secondary sources.
Case studies involving malaria. |
Recall that infectious diseases are caused by
pathogens (disease-causing microorganisms). Recall one example of a disease caused by each type of pathogen limited to athlete’s foot (fungi), flu (viruses), cholera (bacteria) and malaria (protozoa). |
Describe how the human body is defended against pathogens:
• skin provides a barrier • blood clotting prevents entry of pathogens • pathogens are trapped by mucus in airways • hydrochloric acid in the stomach kills pathogens.
Describe the difference between infectious and noninfectious diseases.
Understand that some disorders have other causes, to include genetic causes. |
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Chart the immunisation programme recommended in the UK for children up to the age of 16.
Carry out the role-playing exercise and data analysis from SATIS 9: The Chinese Cancer Detectives.
Use a world map to plan holidays and estimate the risk of exposure to diseases such as malaria, cholera, hepatitis, polio and typhoid. |
Recall that immunisation (vaccination) gives protection from certain pathogens.
Describe how pathogens that enter the body are destroyed by the immune system (white blood cells):
• engulfed by white blood cells • destroyed by antibodies.
Interpret data on the incidence of disease around the world to show links with climate and socio-economic factors. |
Explain why new medical treatments/drugs are tested before use. |
Module B1: Understanding Organisms
Item B1c: Staying healthy
Links to other items: B3b Proteins and mutations, B6a Understanding microbes, B6b Harmful microorganisms
Assessable learning outcomes both tiers: standard demand |
Assessable learning outcomes Higher Tier only: high demand |
Recall the meaning of the terms parasite and host with reference to malaria.
Describe how vectors spread disease:
• limited to mosquito. |
Explain how knowledge of the life cycle of a disease and the way in which vectors spread disease can help control infections:
• limited to malaria and the mosquito. |
Describe changes in lifestyle and diet which may reduce the risk of some cancers. |
Describe the difference between benign and malignant tumours. Interpret data on types of cancer and survival/ mortality rates. |
Explain how pathogens cause the symptoms of an infectious disease by cell damage or by production of toxins.
Recall that antibodies lock on to antigens leading to the death of the pathogens.
Explain the difference between passive (receive antibodies) and active immunity (make own antibodies).
Recall the difference between antibiotics and antiviral drugs. |
Explain how each pathogen has its own antigens so specific antibodies are needed.
Explain the process of immunisation (vaccination):
• harmless pathogen given which carries antigens • antigens trigger immune response by white blood cells which produce antibodies • immunity remains (memory cells produced).
Describe the benefits and risks (possible side effects) associated with immunisation.
Explain the need for careful use of antibiotics to prevent the increase of resistant strains such as MRSA. |
Describe how new treatments are tested using animals, human tissue and computer models and understand objections to some forms of testing. |
Explain why blind and double blind trials are used in testing new drugs against placebos or the best existing treatment. |
Module B1: Understanding Organisms
Item B1d: The nervous system
Summary: Our bodies have to respond to changes that happen both inside and outside the body. The nervous system plays a major part in this. This item provides the opportunity to collect and analyse primary scientific data when investigating density of nerve endings in different skin areas and secondary data when researching reaction times in races. Theories and ideas can be tested in the investigation of binocular vision. This item develops safe and accurate work skills, along with analysis of ideas.
Suggested practical and research activities to select from |
Assessable learning outcomes Foundation Tier only: low demand |
Carry out an experiment to test ranges of vision using cardboard marked out in degrees or moving outstretched arms forward.
Demonstrate binocular vision by bringing pencil points together at arm’s length using one then two eyes. |
Describe how animals detect changes in their environment (stimuli) using receptors which generate nerve impulses.
Name and locate the main parts of the eye: cornea, iris, pupil, lens, retina, optic nerve and blind spot. |
Investigate why some animals have binocular vision and others do not. |
Explain the advantages and disadvantages of:
• monocular vision: wider field of view but poorer judgement of distance • binocular vision: narrower field of view but better judgement of distance. |
Carry out a survey on eye defects (candidates wearing glasses/contact lens) or use second hand data, in class or year group.
Use colour vision deficiency charts. |
Describe the main problems in vision limited to longsight, short-sight and red-green colour blindness. |
Carry out an experiment using blunt needles or forceps to determine the density of nerve endings in different skin areas.
Carry out experiments on reaction times using ICT.
Research allowable reaction times in races. |
Name and locate the main parts of the nervous system, to include:
• the central nervous system (CNS) (brain and spinal cord) • the peripheral nervous system.
Describe the nerve impulse as an electrical signal that is carried by nerve cells called neurones.
Describe reflex actions as fast, automatic and protective responses.
Recognise that voluntary responses are under the conscious control of the brain. |
Module B1: Understanding Organisms
Item B1d: The nervous system
Links to other items: B1e: Drugs and you, B1g: Controlling plant growth, B2e: Adaptations
Assessable learning outcomes both tiers: standard demand |
Assessable learning outcomes Higher Tier only: high demand |
Describe the functions of the main parts of the eye:
• cornea – refracts light • iris – controls how much light enters pupil • lens – focuses light on to retina • retina – contains light receptors, some sensitive to light of different colours • optic nerve – carries impulses to the brain.
Describe the pathway of light through the eyeball, being refracted by the cornea and lens and brought to focus on the retina. |
Explain how the eye focuses light (accommodation) from near and distant objects. |
Explain how binocular vision helps to judge distances by comparing the images from each eye – the more similar the images, the further away the object. |
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Explain how long and short-sight is caused by the eyeball or the lens being the wrong shape. Explain a cause of red-green colour blindness as the lack of specialised cells in the retina. |
Explain how long and short-sight can be corrected by corneal surgery or by different lenses in glasses or contact lenses. |
Name and locate the parts of a motor neurone: cell body, axon and sheath.
Recall that the nerve impulse passes along the axon of a neurone.
Describe a reflex arc:
stimulus → receptor → sensory neurone → central nervous system → motor neurone → effector → response.
Describe the path taken by a spinal reflex involving a receptor, sensory neurone, relay neurone, motor neurone and effector. |
Explain how neurones are adapted to their function by their length, insulating sheath and branched endings (dendrites).
Recall that the gap between neurones is called a synapse.
Describe how an impulse triggers the release of a transmitter substance in a synapse and how it diffuses across to bind with receptor molecules in the membrane of the next neurone causing the impulse to continue.
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Module B1: Understanding Organisms
Item B1e: Drugs and you
Summary: Candidates are exposed to many influences that encourage their natural urge to experiment. This item considers the scientific knowledge and explanations of drugs, their effects and the risks involved. Many drugs are also used legitimately and some of these are considered. This item provides the opportunity to find out about the use of contemporary scientific and technological developments in the detection and analysis of different drugs used in sport. Data from secondary sources can be collected and analysed using ICT tools. There is the opportunity to discuss how scientific knowledge and ideas change over time when investigating the link between smoking and lung cancer.
Suggested practical and research activities to select from |
Assessable learning outcomes Foundation Tier only: low demand |
Arrange a visit from the relevant police departments or rehabilitation centres. |
Recognise that drugs can be beneficial or harmful.
Explain why some drugs are only available on prescription.
Explain the terms: addiction, withdrawal symptoms, tolerance and rehabilitation. |
Research the drug testing programmes in sport. Research and present information about the effects of different drugs on the body. |
Describe the general effects of each drug category:
• depressants: slow down brain’s activity • pain killers: block nerve impulses • stimulants: increase brain’s activity • performance enhancers: muscle development • hallucinogens: distort what is seen and heard. |
Carry out the smoking machine experiment to compare high, medium and low tar brands.
Research a time line of the link between smoking and lung cancer.
Discuss the current anti-smoking laws. |
Recall that tobacco smoking can cause emphysema, bronchitis, cancer (mouth, throat, oesophagus and lung) and heart disease.
Describe the effects of:
• carbon monoxide (lack of oxygen, heart disease) • nicotine (addictive) • tars (irritant, carcinogenic) • particulates (accumulation in lung tissue). |
Produce a poster to warn drivers about the dangers of drink driving. |
Recognise the short term and long term effects of alcohol on the body:
• short term (impaired judgment, balance and muscle control, blurred vision, slurred speech, drowsiness and increased blood flow to the skin) • long term effects (liver and brain damage). Explain why there is a legal limit for the level of alcohol in the blood/breath for drivers and pilots. |
Module B1: Understanding Organisms
Item B1e: Drugs and you
Links to other items: B1a: Fitness and health, B1b: Human health and diet, B1d: The nervous system, B5d: Respiratory systems, B5f: Waste disposal
Assessable learning outcomes both tiers: standard demand |
Assessable learning outcomes Higher Tier only: high demand |
Explain the basis of the legal classification of drugs:
• Class A being the most dangerous with the heaviest penalties
• Class C being the least dangerous with the lightest penalties. |
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Recall examples of drugs:
• depressants, limited to alcohol, solvents and temazepam • pain killers, limited to aspirin and paracetamol • stimulants, limited to nicotine, ecstasy and caffeine • performance enhancers, limited to anabolic steroids • hallucinogens, limited to LSD. |
Explain the action of depressants and stimulants on the synapses of the nervous system:
• depressants bind with receptor molecules in the membrane of the next neurone blocking the transmission of the impulses • stimulants cause more neurotransmitter to cross the synapse. |
Describe how cigarette smoke affects ciliated epithelial cells lining the trachea, bronchi and bronchioles.
Explain why damage to ciliated epithelial cells can lead to a ‘smokers cough’. |
Evaluate data on the effects of smoking in populations (to include, cancer, heart disease, emphysema and birth weights of babies born to mothers who smoke). |
Interpret data on the alcohol content (measured in units of alcohol) of different alcoholic drinks.
Interpret information on reaction times, accident statistics and alcohol levels. |
Describe how the liver can become damaged as it removes alcohol (cirrhosis), to include:
• enzymes in liver breakdown alcohol • toxic products of alcohol breakdown cause liver damage |
Module B1: Understanding Organisms
Item B1f: Staying in balance
Summary: Many complex chemical processes take place in our cells and organs to ensure an optimum state. This item looks at how a constant internal environment is achieved. This item provides the opportunity to collect and analyse primary data and present information using scientific and mathematical conventions in the ‘changing skin temperatures’ experiment. The use of a data logger can provide an opportunity to use an ICT tool. Discussing the use of thermal blankets as a contemporary application of science, along with work on heat stroke, provides the opportunity to look at the benefits of technological developments.
Suggested practical and research activities to select from |
Assessable learning outcomes Foundation Tier only: low demand |
Discuss automatic control systems in candidates’ lives e.g. central heating, air conditioning, cruise control in cars, incubators. |
Recognise that the body works to maintain steady levels of temperature, water, and carbon dioxide and that this is essential to life. |
Carry out an experiment on the changing skin temperature down an arm or a leg and plot the results accurately on a graph.
Measure body temperature using a range of different procedures.
Discuss the use of thermal first aid blankets after activities such as marathons.
Produce a poster warning older people about hypothermia and telling them how to prevent it. |
Recall that the core temperature of the human body is normally maintained at approximately 37°C.
Describe appropriate procedures to measure body temperature:
• where (ear, finger, mouth, or anus) • how (using a clinical thermometer, sensitive strips, digital recording probes, or thermal imaging).
Describe how heat can be gained or retained (by respiration, shivering, exercise, less sweating, less blood flow near skin surface, or clothing).
Describe how more heat can be lost (by sweating, or more blood flow near skin). |
Research diabetes and how it can be managed. |
Name and locate the pancreas.
Recall that the pancreas produces the hormone insulin.
Recall that Type 1 diabetes is caused by the failure of the pancreas to produce insulin. Describe how insulin travels around the body. |
Module B1: Understanding Organisms
Item B1f: Staying in balance
Assessable learning outcomes both tiers: standard demand |
Assessable learning outcomes Higher Tier only: high demand |
Understand that maintaining a constant internal environment involves balancing bodily inputs and outputs and is called homeostasis.
Explain why factors are kept at steady levels by automatic control systems (limited to temperature, water content and carbon dioxide). |
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Explain how sweating increases heat transfer to the environment by evaporation of sweat which requires heat, so removing heat from the skin.
Understand that the body temperature of 37°C is the optimum temperature for the action of many enzymes.
Describe how high temperatures can cause heat stroke and dehydration and if untreated, death.
Describe how very low temperatures can cause hypothermia and if untreated, death. |
Explain how vasodilation and vasoconstriction increase or reduce heat transfer to the environment.
Understand that the body temperature of 37°C is linked to enzyme action.
Explain how blood temperature is monitored by the brain which will bring about temperature control mechanisms via the nervous and hormonal systems. |
Recall that insulin controls blood sugar levels. Explain how Type 2 diabetes can often be controlled by diet but that Type 1 diabetes also needs to be treated by insulin dosage.
Explain why responses controlled by hormones are usually slower than responses controlled by the nervous system. |
Explain how insulin helps to regulate blood sugar levels.
Explain how the dosage of insulin needed to be taken by a person with Type 1 diabetes depends upon diet and activity. |
Module B1: Understanding Organisms
Item B1g: Controlling plant growth
Summary: Growth and development in plants are controlled by plant growth regulators (hormones). This item examines some examples of this, as well as how humans can use plant hormones to aid the efficient production of food. Experiments on seed growth allow the development of safe and accurate working, the presenting of results and evaluation of data collection and the quality of the data.
Suggested practical and research activities to select from |
Assessable learning outcomes Foundation Tier only: low demand |
Carry out an experiment to test whether cress seedlings grow towards light.
Carry out an experiment to test whether bean roots always grow downwards.
Use ICT to watch and compare time lapse videos of plant tropisms. |
Recognise that plants as well as animals respond to changes in their environment.
Understand that plant growth (limited to growth of shoots and roots, flowering and fruit ripening) is controlled by chemicals called plant hormones.
Describe an experiment to show that shoots grow towards light.
Understand how growth towards light increases the plant’s chance of survival.
Understand why roots grow downwards. |
Take cuttings using rooting powder to encourage root growth.
Research how seedless grapes are produced. Investigate bananas ripening more quickly if alreadyripened bananas are close by; research why this happens. |
Recognise that plant hormones can be used in agriculture to speed up or slow down plant growth. |
Module B1: Understanding Organisms
Item B1g: Controlling plant growth
Assessable learning outcomes both tiers: standard demand |
Assessable learning outcomes Higher Tier only: high demand |
Describe shoots as positively phototropic but negatively geotropic.
Describe roots as negatively phototropic but positively geotropic.
Recall that the group of plant hormones called auxins:
• move through the plant in solution • are involved in the response to light (phototropism) • are involved in the response to gravity (geotropism). |
Interpret data from phototropism experiments in terms of auxin action:
• auxin made in tip • unequally distributed in response to light.
Explain how auxin brings about shoot curvature in terms of cell elongation. |
Relate the action of plant hormones to their commercial uses:
• selective weedkillers • rooting powder • fruit ripening (delay or acceleration) • control of dormancy. |